Meloxicam: reviews, prices, analogues. Injections "Meloxicam"
For the treatment of multiple lesions and diseases of the joints and spine, for the relief of pain and inflammatory syndromes nonsteroidal anti-inflammatory drugs are most often used. One of their representatives is Meloxicam. Reviews of patients and doctors indicate a high efficacy of this drug.
Meloxicam is available in tablets and ampoules. At the beginning of the inflammatory process, when pain is expressed, and there are manifestations of inflammation, it is necessary to apply injections to Meloxicam. Reviews indicate a good quick positive effect when using this drug. Tablets are used mainly after relieving acute manifestations of diseases such as:
- rheumatoid arthritis;
- ankylosing spondylitis;
- other degenerative and inflammatory diseases of large and small joints.
All these diseases are characterized by inflammation, pain, degenerative processes in the joints. And such treatment is necessary to eliminate all these unpleasant symptoms that can lead to immobility and disability.
The main active ingredient is meloxicam - a new selective nonsteroidal anti-inflammatory drug that is derived from enolic acid. This substance is able to block the formation and inhibit cyclooxygenase-2, which promotes the production of inflammatory substances - prostaglandins.
If the amount of the drug is small, then it does not act on COX-1, and this leads to inhibition of many side effects. That is, there is no bronchospasm, pain in the ears, fluid retention in the body and inflammatory and destructive diseases of the stomach and the initial sections of the small intestine with subsequent bleeding.
The advantages of "Meloxicam"
A good therapeutic effect is observed when using Meloxicam for the treatment of inflammatory and destructive joint diseases. Instructions for use, reviews of doctors indicate thatthat the drug not only helps to eliminate pain in case of joint diseases, but also interacts well with other medical preparations, without causing gastritis and peptic ulcer disease. In clinical studies, a chondroprotective effect was detected when Meloxicam pricks were used. Reviews of researchers prove that partial restoration of cartilage is possible, which is confirmed by MRI and arthroscopy.
The negative effect of NSAIDs
Osteoarthritis, rheumatism, polyarthritis and other diseases most often affect the elderly, who in addition to these diseases have a whole list of associated illnesses. Therefore, it becomes a problem for doctors to choose the right combination of drugs in order to prevent adverse side effects and to combine one group of drugs with others.
Often, in the treatment of arthritis, medications are simultaneously prescribed to prevent the onset of ulcers and erosions of the stomach and cardiovascular disorders, restore diuresis and reduce puffiness. Some NSAIDs (nonsteroidal anti-inflammatory drugs) have an adverse effect on the cartilage layer of the joint.That is, the pain goes away, but the therapeutic effect is canceled due to the destruction of the articular cartilage under the influence of these drugs.
For example, indomethacin was excluded from the list of healing NSAIDs, as it stimulates the destructive processes of cartilage tissue in the elderly. But non-steroids ("Diclofenac", "Ketanov", etc.) must be used constantly for quite a long time. And their dosage is much higher than that of the Meloxicam preparation. Reviews of doctors confirm this.
Interaction with other drugs
New selective non-steroidal anti-inflammatory drugs, such as Meloxicam, have a more favorable effect. Instructions, reviews of practitioners confirm that in small dosage of the drug does not affect the blood flow in the vessels, kidneys and heart muscle, the side effects are minimal. At the same time, Meloxicam interacts well with cardiac glycosides, cytostatics, diuretics, and other drugs. All this allows you to prescribe a rational and adequate therapy for the treatment of elderly people and patients with concomitant diseases using Meloxicam.Reviews of patients - a direct confirmation of this.
The drug is well absorbed and tolerated by oral administration and intramuscular administration of the drug. The analgesic effect occurs after 15–20 minutes, and the maximum concentration in the blood occurs after 6 hours. Moreover, Meloxicam binds well to blood proteins, which accelerates the process of drug delivery to the affected organ. The greatest concentration of the drug is observed in the fluid articular bags. This, in particular, explains the reducing effect of Meloxicam.
Neutralization and disintegration of the drug occurs in the liver. At the same time, non-aggressive and inactive substances are formed, which are excreted by the kidneys and intestines.
How to use the drug
Treatment of osteoarthrosis, polyarthritis, arthritis, radiculopathy, and other diseases of the joints should be started with a loading dose of 15 mg. The best introduction is intramuscular at a dose of 15 mg. 1 vial of solution contains just such a dosage, and therefore one injection per day is sufficient. It is recommended to spend for three days, and then switch to oral medication: 1 tablet 7.5 mg per day with meals. You should consider the age of the patient, the presence of diseases and contraindications.In each case, the doctor selects the dosage. Most often enough and 7.5 mg per day. If the therapeutic effect does not occur, then overdosing will not lead to the desired result. Do not combine the drug with other NSAIDs.
Each drug from the group of NSAIDs has a side effect. Has such actions and "Meloxicam". However, if you read the instructions, all unwanted effects are written with the word "infrequently":
- constipation, flatulence, esophagitis, colitis, hepatitis, gastritis, etc .;
- anemia, leukocyte shift, leukopenia, thrombocytopenia;
- urticaria, rash, erythema, dermatitis;
- tinnitus, disorientation, confusion;
- increased blood pressure, palpitations, "hot flashes";
- increased urea in the blood, acute renal failure;
- conjunctivitis, blurred vision, blurred perception;
- anaphylactic reactions and angioedema.
Nausea, vomiting, constipation, diarrhea - these are the undesirable effects that occur when taking any drug.
The use of "Meloxicam" is contraindicated:
- with intolerance to the components of the drug: active ingredient, starch, lactose, aerosil, cellulose, silicon dioxide, sodium citrate and magnesium stearate;
- any bleeding: gastric, intestinal;
- with stroke and heart attack;
- hepatic and renal failure;
- with bronchial asthma;
- with polyposis;
- pregnant and lactating;
- children up to 15 years.
You should not drink alcohol during treatment with meloxicam.
Cost of the drug
Doctors say that an effective solution for injections "Meloxicam" (shots). The price (testimonials from patients who purchased this drug, indicate) varies from 150 to 200 rubles. But nothing worse than the means in the form of tablets. Both doctors and patients speak in favor of this particular drug when choosing from all anti-inflammatory drugs: a good analgesic effect, a minimum of side effects and accessibility (a blister of 10 tablets costs from 60 to 120 rubles).
What can replace "Meloxicam"
The drug is manufactured by 13 pharmaceutical companies in Russia. Other countries that produce "Meloxicam" - China, Greece, Israel, USA, India, Vietnam.
In the treatment are used and drug substitutes "Meloxicam" - analogues. Reviews show that they have a good anti-inflammatory and analgesic effect.These are "Hondroksid Forte", "Liberum", "Amelotex".
Drugs that contain meloxicam - Movalis, Movix, Oxycamox, Mirlox, Matarin, Meloflam, Movasin, Medsikam and others.
Only these drugs act in the same way as "Meloxicam", and in each particular case this or that drug is prescribed by a doctor. This takes into account the indications, concomitant diseases, compatibility with other drugs. You should never choose your own medicine and self-medicate, since interaction with other medicines leads to undesirable consequences.
Compatibility with other drugs
When prescribing a treatment, the doctor takes into account undesirable consequences that the combination of "Meloxicam" with other medications can cause:
- gastric bleeding is possible with NSAIDs, anticoagulants, and selective inhibitors;
- with drugs that reduce pressure - the weakening of the hypotensive effect;
- with lithium preparations - difficulty in removing lithium;
- anemia of III degree and leukopenia possible with methotrexate;
- with cyclosporine and diuretics, the likelihood of renal failure is high;
- weakening of the contraceptive effect of intrauterine contraceptives.
Doctors advise patients with osteoarthritis and other diseases of the musculoskeletal system to be treated with the drug "Meloxicam": price, reviews, analogues confirm the high therapeutic efficacy of the drug, despite the presence of side effects.